Brand New Day is a comic book storyline published by Marvel Comics in The Amazing Spider-Man, spanning issues #546 to #564 from January to July 2008. Written by a team including Dan Slott, Marc Guggenheim, Bob Gale, and Zeb Wells, with art by various artists such as Steve McNiven, it marked a major reset for the Spider-Man series following the controversial One More Day storyline. In this era, Peter Parker's marriage to Mary Jane Watson is retroactively erased by a deal with Mephisto, restoring him to single life and adjusting his personal history while he resumes web-slinging in New York City after a 100-day absence amid the Superhuman Registration Act.
The narrative focuses on Spider-Man's street-level adventures, introducing new characters like Mister Negative, Menace, and Jackpot, alongside returns of familiar foes and allies such as Harry Osborn. Emphasizing Peter Parker's perpetual bad luck, financial struggles, and romantic entanglements, the storyline revitalized the series with shorter, self-contained arcs and a back-to-basics approach. It ran for over 100 issues until transitioning into Spider-Man: Big Time, influencing subsequent Spider-Man comics and becoming a benchmark for character reboots in superhero publishing.